"Would you like to help kids born with severe heart defects have better lives while also doing exciting science?

The Nigam Lab (at the Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute and the Department of immunology, University of Washington invites applications for a Postdoctoral Fellow position. Work in the Nigam lab uses basic science and translational approaches to improve the care of children born with severe cardiac defects. The primary focus of the lab seeks to elucidate and find novel treatments for the systemic inflammation that occurs after exposure to cardiopulmonary bypass, which is required for the majority of cardiac surgeries. This project, which has been recently awarded a R01, examines how biomechanical stimuli activate inflammatory responses. Previous Research Scientists in the lab have been coauthors on a number of papers. Given the rapid progress of the project, there is a very good potential to be an author on high impact papers.

The successful candidate will perform laboratory procedures as part of ongoing research studies; assist in planning research experiments, their execution and data analysis; assist others in the laboratory with problem-solving and understanding molecular biology; and help maintain a constructive laboratory environment.The candidate will work closely with a post-doc and graduate/undergraduate students to plan and supervise several parallel lines of investigation.

Perform laboratory procedures as part of ongoing research studies; assist in planning research experiments, their execution and data analysis; assist others in the laboratory with problem-solving and understanding molecular biology; and help maintain a constructive laboratory environment.

The selected candidate will join the vibrant research community at CDBRMand Department of immunology, located in a newly renovated building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment.

The University of Washington andSeattle Children's Research Institutehave strong scientific interactions with Fred Hutchinson Cancer Research Center, Benaroya Research Institute, Institute for Systems Biology, and Brain Research Institute.

Interested applicants should email their CV and briefdescriptionof research interests in single PDF file to."

Required Education/Experience:

• Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program.

• Experience using basic research techniques of specialty area.

Required Credentials:

• N/A.

Preferred:

• Previous experience conducting research in the pediatric arena.

• Experience in protocol and manuscript development and in grant writing.

This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.

This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors.

Seattle Children's offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. for more information.

Hope. Care. Cure. These three simple words capture what we do at Seattle Children's - to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.

Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine.

Researchers work in close collaboration with one another, their colleagues at partner institutions including theandand our healthcare providers at Seattle Children's Hospital, one oftop children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.